BRWD3

Across TCGA patient cohorts, BRWD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,973 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRWD3-associated proteins across cancer lineages are HNRNPH2, HTATSF1, and NONO. Each is linked with BRWD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both BRWD3-to-partner and partner-to-BRWD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRWD3 versus HNRNPH2 in HNSC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRWD3→partner) and Y-score (partner→BRWD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HNRNPH2 →	+0.220	+0.530	.001	<.001	3	6
GBM	HTATSF1 →	+0.444	+0.493	<.001	<.001	3	6
GBM	NONO →	+0.188	+0.381	<.001	<.001	3	5
HNSC	PHF6 →	+0.463	+0.663	<.001	<.001	3	5
HNSC	CUL4B →	+0.315	+0.685	<.001	<.001	3	5
LSCC	DHX9 →	+0.229	+0.400	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,973 associations by consensus.

BRWD3 vs HNRNPH2 — HNSC

Explore this scatter interactively →