BRWD3

Across TCGA patient cohorts, BRWD3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,290 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRWD3-associated genes across cancer lineages are SAMD12, ASGR2, and RPS6KA1. Each is linked with BRWD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both BRWD3-to-partner and partner-to-BRWD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRWD3 versus SAMD12 in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRWD3→partner) and Y-score (partner→BRWD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SAMD12 →	+1.050	+0.672	.006	.006	3	3
GBM	ASGR2 →	-0.321	-0.370	.004	.002	3	3
BRCA	RPS6KA1 →	-0.704	-0.821	<.001	<.001	3	2
GBM	SOX4 →	+1.499	+0.621	<.001	<.001	3	2
BRCA	LRCH2 →	+0.912	+1.000	.004	.003	3	2
BRCA	FBXO44 →	-0.629	-0.764	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,290 associations by consensus.

BRWD3 vs SAMD12 — BRCA

Explore this scatter interactively →