Across TCGA patient cohorts, BRWD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,664 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRWD1-associated proteins across cancer lineages are GBF1, HMGN1, and TCEAL1. Each is linked with BRWD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BRWD1-to-partner and partner-to-BRWD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRWD1→partner) and Y-score (partner→BRWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GBF1 →	-0.202	-0.437	<.001	<.001	3	5
BRCA	HMGN1 →	+0.622	+0.660	<.001	<.001	3	5
BRCA	TCEAL1 →	+0.506	+0.467	<.001	<.001	3	5
GBM	RPRD2 →	+0.328	+0.469	<.001	<.001	3	4
GBM	TBXAS1 →	-0.474	-0.361	.002	<.001	3	4
PDAC	TJP3_S164 →	+0.689	+0.191	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,664 associations by consensus.

Exploration

BRWD1 survival (RNA) · tumor vs normal (RNA) · all BRWD1 data types