Across TCGA patient cohorts, BRWD1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,021 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BRWD1-associated genes across cancer lineages are UBE2G2, NDUFV3, and SLC25A15. Each is linked with BRWD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BRWD1-to-partner and partner-to-BRWD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRWD1→partner) and Y-score (partner→BRWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UBE2G2 →	+0.809	+0.438	.003	.002	3	4
LSCC	NDUFV3 →	+0.406	+0.392	<.001	<.001	3	4
LSCC	SLC25A15 →	+0.659	+0.358	<.001	<.001	3	4
OV	NFYA →	+1.098	+0.441	.003	.003	3	3
OV	AMMECR1L →	+0.991	+0.539	.003	.001	3	3
OV	CCDC150 →	+1.021	+0.538	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,021 associations by consensus.

Exploration

BRWD1 survival (RNA) · tumor vs normal (RNA) · all BRWD1 data types