BRWD1-AS1

Across TCGA pan-cancer cohorts, BRWD1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated BRWD1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BRWD1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BRWD1-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and HNSC show a favorable association.

KIRC, PAAD, and KICH are the cancer types where BRWD1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.557	0.736	<.001	101	view →
PAAD	DFS	Median	All	0.392	0.191	<.001	48	view →
KICH	DFS	Median	All	0.692	0.974	.001	44	view →
HNSC	DFS	Quartile	IV	0.781	0.586	.004	38	view →
UVM	DFS	Median	All	0.381	0.716	.015	31	view →
LIHC	DFS	Quartile	All	0.297	0.475	.004	25	view →
ACC	DFS	Tertile	All	0.133	0.524	.001	21	view →
READ	DFS	Tertile	III,IV	0.320	0.732	.009	15	view →
DLBC	OS	Quartile	All	1.000	0.476	.016	15	view →
COAD	OS	Tertile	II,III,IV	0.802	0.874	.008	14	view →
UCS	OS	Median	II,III,IV	0.689	0.324	.003	12	view →
SKCM	OS	Quartile	III,IV	0.667	0.865	.005	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

BRWD1-AS1–KIRC (DFS)

Open the KIRC breakdown →