BRSK2

Across TCGA patient cohorts, BRSK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,209 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRSK2-associated proteins across cancer lineages are SEC24A, SNAP23, and PPIB. Each is linked with BRSK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both BRSK2-to-partner and partner-to-BRSK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRSK2 versus SEC24A in LSCC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRSK2→partner) and Y-score (partner→BRSK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SEC24A →	-0.259	-0.361	<.001	<.001	3	5
GBM	SNAP23 →	-0.263	-0.762	<.001	<.001	3	5
LSCC	PPIB →	-0.337	-0.399	<.001	<.001	3	4
LSCC	TMEM165 →	-0.475	-0.616	<.001	<.001	3	4
CCRCC	TMF1 →	-0.243	-0.307	<.001	<.001	3	4
GBM	UBA7 →	-0.378	-0.820	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,209 associations by consensus.

BRSK2 vs SEC24A — LSCC

Explore this scatter interactively →