BRSK1

Across TCGA patient cohorts, BRSK1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,980 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRSK1-associated genes across cancer lineages are CDKN3, CAB39L, and CRYM. Each is linked with BRSK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRSK1-to-partner and partner-to-BRSK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRSK1 versus CDKN3 in LSCC, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRSK1→partner) and Y-score (partner→BRSK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDKN3 →	-1.423	-0.581	.007	.001	3	2
BRCA	CAB39L →	+1.405	+0.953	.004	.005	3	2
GBM	CRYM →	+1.555	+0.581	<.001	<.001	3	2
GBM	STMN2 →	+2.544	+0.539	<.001	<.001	3	2
LSCC	ASF1B →	-1.672	-0.670	.002	.001	3	2
BRCA	HAS1 →	+0.648	+0.877	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,980 associations by consensus.

BRSK1 vs CDKN3 — LSCC

Explore this scatter interactively →