BRS3

Across TCGA patient cohorts, BRS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,109 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BRS3-associated proteins across cancer lineages are HEXIM2_S76, HTATSF1, and RPS3_T221. Each is linked with BRS3 in more than 2 cancer types. Because this analysis shows association rather than direction, both BRS3-to-partner and partner-to-BRS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRS3 versus HEXIM2_S76 in PDAC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRS3→partner) and Y-score (partner→BRS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HEXIM2_S76 →	+0.907	+0.537	.003	.003	3	3
LSCC	HTATSF1 →	+0.300	+0.144	.004	.001	3	3
GBM	RPS3_T221 →	-0.430	-0.155	.003	.003	3	3
BRCA	DPY19L3 →	-0.522	-0.094	<.001	.001	3	3
HNSC	OCRL →	+0.247	+0.203	<.001	.007	3	3
HNSC	TPMT_S229 →	+0.485	+0.228	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,109 associations by consensus.

BRS3 vs HEXIM2_S76 — PDAC

Explore this scatter interactively →