BRPF3

Across TCGA patient cohorts, BRPF3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,435 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible BRPF3-associated genes across cancer lineages are SUMO3, THAP12P8, and FBXO25. Each is linked with BRPF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRPF3-to-partner and partner-to-BRPF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRPF3 versus SUMO3 in OV, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRPF3→partner) and Y-score (partner→BRPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SUMO3 →	+0.947	+0.827	<.001	<.001	3	2
LUAD	THAP12P8 →	+0.324	+0.182	.007	.004	3	2
CCRCC	FBXO25 →	-0.479	-0.373	.008	.007	3	2
UCEC	MIR660 →	+0.839	+0.158	.008	.003	3	2
HNSC	GLRA1 →	-0.375	-0.945	.004	.003	3	2
HNSC	SYT8 →	-1.385	-0.626	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,435 associations by consensus.

BRPF3 vs SUMO3 — OV

Explore this scatter interactively →