BRPF1

Across TCGA cell cohorts, BRPF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,437 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BRPF1-associated GO terms across cancer lineages are Spindle localization, Epigenetic regulation of gene expression, and Nuclear export. Each is linked with BRPF1 in more than 17 cancer types. Because this analysis shows association rather than direction, both BRPF1-to-partner and partner-to-BRPF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle localization grouped by BRPF1-low versus BRPF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRPF1→partner) and Y-score (partner→BRPF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Spindle localization →	+0.118	+0.858	<.001	<.001	3	18
BONE	Epigenetic regulation of gene expression →	+0.068	+0.762	.001	<.001	2	18
SOFT_TISSUE	Nuclear export →	+0.110	+1.276	<.001	<.001	3	17
SOFT_TISSUE	RNA export from nucleus →	+0.139	+1.198	<.001	<.001	3	17
SOFT_TISSUE	Establishment of mitotic spindle localization →	+0.139	+1.076	<.001	<.001	3	17
BONE	Mitotic chromosome condensation →	+0.157	+0.842	.005	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,437 associations by consensus.

Spindle localization by BRPF1 expression — BONE

Explore this box plot interactively →