BRMS1

Across TCGA pan-cancer cohorts, BRMS1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated BRMS1 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BRMS1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BRMS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, LUAD, and LSCC are the cancer types where BRMS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	1.000	0.247	.008	32	view →
LUAD	DFS	Median	All	1.000	0.618	<.001	12	view →
LSCC	OS	Median	II,III,IV	1.000	0.905	.022	7	view →
GBM	DFS	Tertile	All	0.855	0.538	.014	6	view →
HNSC	OS	Median	All	1.000	0.955	.023	2	view →
PDAC	DFS	Median	All	0.508	0.348	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

BRMS1–UCEC (DFS)

Open the UCEC breakdown →