BRMS1

Across TCGA patient cohorts, BRMS1 mutation is significantly associated with the RNA expression of many other genes, with 793 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BRMS1-associated genes across cancer lineages are RNA5SP113, VENTXP3, and RN7SL568P. Each is linked with BRMS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BRMS1-to-partner and partner-to-BRMS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP113 grouped by BRMS1-low versus BRMS1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRMS1→partner) and Y-score (partner→BRMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP113 →	+0.237	+4.618	<.001	.005	3	3
CESC	VENTXP3 →	+0.044	+4.812	<.001	.006	3	2
SKCM	RN7SL568P →	+0.110	+4.513	<.001	.009	3	2
SKCM	ATP5MGP7 →	+0.111	+4.867	<.001	.005	3	2
BLCA	RNU6-177P →	+0.365	+4.038	.001	.002	3	2
HNSC	MIR6718 →	+0.368	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 793 associations by consensus.

RNA5SP113 by BRMS1 expression — BLCA

Explore this box plot interactively →