BRMS1

Across TCGA cell cohorts, BRMS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,713 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BRMS1-associated GO terms across cancer lineages are Mitotic spindle midzone assembly, Mitotic spindle elongation, and Spindle midzone assembly. Each is linked with BRMS1 in more than 12 cancer types. Because this analysis shows association rather than direction, both BRMS1-to-partner and partner-to-BRMS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle midzone assembly grouped by BRMS1-low versus BRMS1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRMS1→partner) and Y-score (partner→BRMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Mitotic spindle midzone assembly →	+0.215	+0.805	<.001	<.001	3	13
PANCREAS	Mitotic spindle elongation →	+0.215	+0.805	<.001	<.001	3	13
PANCREAS	Spindle midzone assembly →	+0.168	+0.691	.003	.001	3	13
UPPER_AERODIGESTIVE_TRACT	CAAX-box protein processing →	+0.123	+0.870	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of metaphase plate congression →	+0.170	+1.091	<.001	<.001	3	12
URINARY_TRACT	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.202	+0.851	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,713 associations by consensus.

Mitotic spindle midzone assembly by BRMS1 expression — PANCREAS

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