BRIX1

Across TCGA patient cohorts, BRIX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,238 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BRIX1-associated proteins across cancer lineages are NSUN2, TRIP13, and KPNA2. Each is linked with BRIX1 in more than 8 cancer types. Because this analysis shows association rather than direction, both BRIX1-to-partner and partner-to-BRIX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRIX1 versus NSUN2 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRIX1→partner) and Y-score (partner→BRIX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NSUN2 →	+0.399	+0.707	<.001	<.001	3	9
LUAD	TRIP13 →	+0.631	+0.504	<.001	<.001	3	9
OV	KPNA2 →	+0.631	+0.527	<.001	.002	3	9
GBM	MCM3 →	+0.642	+0.333	.001	<.001	3	9
GBM	MCM4 →	+0.616	+0.312	<.001	.002	3	9
GBM	MCM5 →	+0.600	+0.340	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,238 associations by consensus.

BRIX1 vs NSUN2 — LSCC

Explore this scatter interactively →