BRIX1

Across TCGA patient cohorts, BRIX1 protein abundance is significantly associated with the RNA expression of many other genes, with 23,028 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BRIX1-associated genes across cancer lineages are CPED1, ABCA8, and DKC1. Each is linked with BRIX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both BRIX1-to-partner and partner-to-BRIX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRIX1 versus CPED1 in COAD, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRIX1→partner) and Y-score (partner→BRIX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CPED1 →	-0.796	-0.252	<.001	<.001	3	8
BRCA	ABCA8 →	-1.350	-0.434	<.001	<.001	3	8
LSCC	DKC1 →	+0.778	+0.350	<.001	<.001	3	7
CCRCC	LMOD1 →	-1.191	-0.267	<.001	.001	3	7
BRCA	FCER1A →	-1.610	-0.459	<.001	<.001	3	7
HNSC	NPM1 →	+0.773	+0.222	.004	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,028 associations by consensus.

BRIX1 vs CPED1 — COAD

Explore this scatter interactively →