BRIX1

Across TCGA cell cohorts, BRIX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,707 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BRIX1-associated GO terms across cancer lineages are Protein localization to nuclear inner membrane, Meiotic recombination checkpoint signaling, and 'de novo' AMP biosynthetic process. Each is linked with BRIX1 in more than 18 cancer types. Because this analysis shows association rather than direction, both BRIX1-to-partner and partner-to-BRIX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nuclear inner membrane grouped by BRIX1-low versus BRIX1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRIX1→partner) and Y-score (partner→BRIX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein localization to nuclear inner membrane →	+0.198	+1.242	<.001	<.001	3	19
OESOPHAGUS	Meiotic recombination checkpoint signaling →	+0.257	+0.918	<.001	<.001	3	19
BONE	'de novo' AMP biosynthetic process →	+0.203	+0.997	<.001	<.001	3	17
OESOPHAGUS	DNA replication checkpoint signaling →	+0.184	+1.128	.002	.001	3	17
BONE	rRNA processing →	+0.107	+0.604	<.001	<.001	3	16
OESOPHAGUS	Protein localization to kinetochore →	+0.147	+0.902	.005	.004	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,707 associations by consensus.

Protein localization to nuclear inner membrane by BRIX1 expression — URINARY_TRACT

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