Across TCGA patient cohorts, BRICD5 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BRICD5-associated genes across cancer lineages are EGFR_pY1068, JNK2, and Ku80. Each is linked with BRICD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRICD5-to-partner and partner-to-BRICD5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRICD5→partner) and Y-score (partner→BRICD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.316	-3.321	.016	.010	3	1
UCEC	JNK2 →	+0.380	+3.009	<.001	.019	3	1
UCEC	Ku80 →	+0.256	+2.183	.039	.035	3	1
UCEC	Notch1 →	+0.198	+3.321	.007	.010	3	1
UCEC	STAT3_pY705 →	-0.470	-3.321	<.001	.010	3	1
UCEC	VEGFR2 →	+0.308	+3.179	.048	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

BRICD5 survival (RNA) · tumor vs normal (RNA) · all BRICD5 data types