BRI3P3

Across TCGA patient cohorts, BRI3P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,423 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BRI3P3-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Protein localization to endoplasmic reticulum, and Protein-RNA complex organization. Each is linked with BRI3P3 in more than 11 cancer types. Because this analysis shows association rather than direction, both BRI3P3-to-partner and partner-to-BRI3P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by BRI3P3-low versus BRI3P3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRI3P3→partner) and Y-score (partner→BRI3P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of DNA metabolic process →	+0.062	+0.201	<.001	<.001	3	11
STAD	Protein localization to endoplasmic reticulum →	+0.063	+0.184	<.001	<.001	3	11
ESCA	Protein-RNA complex organization →	+0.072	+0.259	<.001	<.001	3	11
ESCA	Establishment of protein localization to endoplasmic reticulum →	+0.061	+0.199	<.001	<.001	3	11
STAD	Positive regulation of organelle assembly →	+0.051	+0.205	<.001	<.001	3	11
ESCA	Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway →	+0.058	+0.229	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,423 associations by consensus.

Positive regulation of DNA metabolic process by BRI3P3 expression — ESCA

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