BRI3BPP1

Across TCGA pan-cancer cohorts, BRI3BPP1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated BRI3BPP1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher BRI3BPP1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated BRI3BPP1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and BLCA show a favorable association.

LUSC, BLCA, and KIRP are the cancer types where BRI3BPP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	III,IV	0.708	0.237	.002	60	view →
BLCA	OS	Median	All	0.564	0.337	.004	44	view →
KIRP	DFS	Median	III,IV	0.853	0.230	.007	38	view →
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	36	view →
UCEC	OS	Quartile	III,IV	0.921	0.788	.010	32	view →
LGG	DFS	Quartile	All	0.608	0.773	<.001	30	view →
HNSC	DFS	Tertile	IV	0.211	0.600	<.001	24	view →
READ	DFS	Tertile	All	0.189	0.615	<.001	21	view →
ACC	DFS	Tertile	II,III,IV	0.819	0.444	.019	19	view →
SKCM	DFS	Tertile	II,III,IV	0.659	0.541	.015	12	view →
MESO	OS	Quartile	All	0.495	0.214	.008	11	view →
KIRC	DFS	Quartile	III,IV	0.634	0.767	.029	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

BRI3BPP1–LUSC (DFS)

Open the LUSC breakdown →