Across TCGA patient cohorts, BRI3BP protein abundance is significantly associated with the RNA expression of many other genes, with 8,876 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BRI3BP-associated genes across cancer lineages are RFC5, COX6A1, and TMPO. Each is linked with BRI3BP in more than 3 cancer types. Because this analysis shows association rather than direction, both BRI3BP-to-partner and partner-to-BRI3BP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRI3BP→partner) and Y-score (partner→BRI3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC5 →	+0.586	+0.323	<.001	.002	3	4
COAD	COX6A1 →	+0.534	+0.404	.001	<.001	3	4
LSCC	TMPO →	+0.701	+0.367	<.001	<.001	3	4
OV	FAM200A →	-0.444	-0.584	<.001	<.001	3	4
COAD	TTLL1 →	-0.356	-0.294	.003	.006	3	3
COAD	TNNC2 →	-1.520	-0.265	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,876 associations by consensus.

Exploration

BRI3BP survival (RNA) · tumor vs normal (RNA) · all BRI3BP data types