Across TCGA patient cohorts, BRI3BP mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible BRI3BP-associated genes across cancer lineages are UBQLN1P1, RNU7-63P, and RNU1-80P. Each is linked with BRI3BP in more than 1 cancer types. Because this analysis shows association rather than direction, both BRI3BP-to-partner and partner-to-BRI3BP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRI3BP→partner) and Y-score (partner→BRI3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	UBQLN1P1 →	+0.043	+5.362	<.001	.005	3	1
SKCM	RNU7-63P →	+0.589	+4.979	<.001	.009	3	1
SKCM	RNU1-80P →	+0.475	+5.970	<.001	.002	3	1
SKCM	GCNT1P2 →	+0.083	+5.159	.008	.007	3	1
SKCM	CCDC37-DT →	+0.051	+5.097	<.001	.008	3	1
KIRP	RPL7L1P1 →	+0.105	+5.264	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

BRI3BP survival (RNA) · tumor vs normal (RNA) · all BRI3BP data types