BRDT

Across TCGA patient cohorts, BRDT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,979 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BRDT-associated GO terms across cancer lineages are DNA-templated transcription initiation, Mitochondrial gene expression, and Protein-RNA complex organization. Each is linked with BRDT in more than 17 cancer types. Because this analysis shows association rather than direction, both BRDT-to-partner and partner-to-BRDT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by BRDT-low versus BRDT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRDT→partner) and Y-score (partner→BRDT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA-templated transcription initiation →	+0.074	+0.346	<.001	<.001	3	18
STAD	Mitochondrial gene expression →	+0.081	+0.418	<.001	<.001	3	17
STAD	Protein-RNA complex organization →	+0.077	+0.380	<.001	<.001	3	17
STAD	Macromolecule methylation →	+0.071	+0.375	<.001	<.001	3	16
STAD	Positive regulation of DNA repair →	+0.065	+0.422	<.001	<.001	3	16
STAD	DNA-templated transcription termination →	+0.069	+0.367	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,979 associations by consensus.

DNA-templated transcription initiation by BRDT expression — STAD

Explore this box plot interactively →