BRDT

Across TCGA patient cohorts, BRDT protein abundance is significantly associated with the RNA expression of many other genes, with 3,289 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible BRDT-associated genes across cancer lineages are DMAC1P1, NINL, and EEF1A2. Each is linked with BRDT in more than 1 cancer types. Because this analysis shows association rather than direction, both BRDT-to-partner and partner-to-BRDT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRDT versus DMAC1P1 in LUAD, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRDT→partner) and Y-score (partner→BRDT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DMAC1P1 →	-0.547	-2.256	.001	.002	3	2
LUAD	NINL →	+0.818	+1.649	.001	.004	3	1
LUAD	EEF1A2 →	-2.414	-1.942	.001	.003	3	1
LUAD	LSR →	+0.486	+1.539	.007	.008	3	1
LUAD	ATP6V0E1 →	-0.780	-2.436	.001	.002	3	1
LUAD	RGSL1 →	+0.076	+2.135	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,289 associations by consensus.

BRDT vs DMAC1P1 — LUAD

Explore this scatter interactively →