Across TCGA pan-cancer cohorts, BRD7P5 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of BRD7P5’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where BRD7P5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BRD7P5 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
UCEC, COAD, and THCA are the cancer types where BRD7P5 tumor–normal differential expression is most reproducible.