Across TCGA pan-cancer cohorts, BRD7P4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of BRD7P4’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where BRD7P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BRD7P4 is over-expressed in tumor, although a few such as PAAD and BRCA show the opposite, repressed pattern.
COAD, PAAD, and BRCA are the cancer types where BRD7P4 tumor–normal differential expression is most reproducible.