BRD1

Across TCGA patient cohorts, BRD1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,542 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BRD1-associated genes across cancer lineages are HERC5, SNHG20, and CENPM. Each is linked with BRD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BRD1-to-partner and partner-to-BRD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRD1 versus HERC5 in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRD1→partner) and Y-score (partner→BRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HERC5 →	-0.901	-0.492	.004	.002	3	4
HNSC	SNHG20 →	+0.692	+0.441	<.001	.001	3	4
LSCC	CENPM →	+0.808	+0.300	<.001	<.001	3	4
LSCC	ZBED4 →	+0.570	+0.295	<.001	<.001	3	4
BRCA	TRIM6 →	-0.808	-0.280	<.001	<.001	3	4
UCEC	C16orf89 →	-1.497	-0.158	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,542 associations by consensus.

BRD1 vs HERC5 — OV

Explore this scatter interactively →