Across TCGA cell cohorts, BRCC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,221 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BRCC3-associated GO terms across cancer lineages are snRNA pseudouridine synthesis, Spindle elongation, and DNA strand elongation. Each is linked with BRCC3 in more than 13 cancer types. Because this analysis shows association rather than direction, both BRCC3-to-partner and partner-to-BRCC3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRCC3→partner) and Y-score (partner→BRCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	snRNA pseudouridine synthesis →	+0.111	+0.621	.009	.002	3	14
SOFT_TISSUE	Spindle elongation →	+0.245	+0.814	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.181	+1.339	<.001	<.001	3	14
BONE	Positive regulation of telomerase RNA localization to Cajal body →	+0.107	+0.618	.007	.004	2	14
KIDNEY	DNA replication initiation →	+0.141	+0.774	<.001	.006	3	13
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.094	+1.656	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,221 associations by consensus.

Exploration

BRCC3 survival (RNA) · tumor vs normal (RNA) · all BRCC3 data types