BRCA1P1

Across TCGA patient cohorts, BRCA1P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BRCA1P1-associated proteins across cancer lineages are RBM12B, DHX9, and LUC7L3. Each is linked with BRCA1P1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BRCA1P1-to-partner and partner-to-BRCA1P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRCA1P1 versus RBM12B in HNSC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRCA1P1→partner) and Y-score (partner→BRCA1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RBM12B →	+0.344	+1.795	<.001	<.001	3	5
LSCC	DHX9 →	+0.364	+1.047	<.001	<.001	3	5
GBM	LUC7L3 →	+0.301	+0.918	.003	.002	3	5
BRCA	HIRIP3_T84 →	+0.486	+0.760	.005	.004	3	5
LSCC	LIG3 →	+0.427	+0.776	<.001	<.001	3	5
GBM	PHF10 →	+0.346	+0.971	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,991 associations by consensus.

BRCA1P1 vs RBM12B — HNSC

Explore this scatter interactively →