BRAT1

Across TCGA patient cohorts, BRAT1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,225 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRAT1-associated genes across cancer lineages are NUDT1, AIMP2, and LSM5. Each is linked with BRAT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both BRAT1-to-partner and partner-to-BRAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRAT1 versus NUDT1 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRAT1→partner) and Y-score (partner→BRAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUDT1 →	+0.814	+0.220	<.001	<.001	3	8
HNSC	AIMP2 →	+0.701	+0.169	<.001	<.001	3	8
OV	LSM5 →	+0.600	+0.247	<.001	.005	3	7
HNSC	EIF3B →	+0.608	+0.171	<.001	<.001	3	7
HNSC	NUP42 →	+0.489	+0.151	<.001	.001	3	6
HNSC	PMS2 →	+0.456	+0.217	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,225 associations by consensus.

BRAT1 vs NUDT1 — HNSC

Explore this scatter interactively →