BPNT2

Across TCGA patient cohorts, BPNT2 mutation is significantly associated with the RNA expression of many other genes, with 1,680 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BPNT2-associated genes across cancer lineages are OR8B10P, DUXAP2, and HMX2. Each is linked with BPNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPNT2-to-partner and partner-to-BPNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B10P grouped by BPNT2-low versus BPNT2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPNT2→partner) and Y-score (partner→BPNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR8B10P →	+0.072	+4.628	<.001	.004	3	2
LUAD	DUXAP2 →	+0.439	+3.048	<.001	.008	3	2
UCEC	HMX2 →	+0.726	+2.509	.001	.001	3	2
UCEC	RN7SL98P →	+0.101	+2.430	.001	.001	3	2
UCEC	LINC02438 →	+0.646	+3.931	<.001	<.001	3	2
UCEC	RNA5SP419 →	+0.577	+2.269	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,680 associations by consensus.

OR8B10P by BPNT2 expression — SKCM

Explore this box plot interactively →