BPNT2

Across TCGA cell cohorts, BPNT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,553 significant associations in total. CNS shows the largest number of these associations.

The most reproducible BPNT2-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, ERAD pathway, and Positive regulation of translational initiation. Each is linked with BPNT2 in more than 11 cancer types. Because this analysis shows association rather than direction, both BPNT2-to-partner and partner-to-BPNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by BPNT2-low versus BPNT2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BPNT2→partner) and Y-score (partner→BPNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of protein exit from endoplasmic reticulum →	+0.152	+1.246	.002	<.001	3	12
CNS	ERAD pathway →	+0.086	+0.847	<.001	<.001	3	12
OESOPHAGUS	Positive regulation of translational initiation →	+0.102	+1.084	.005	<.001	3	12
BLOOD_Lymphoma	Nuclear membrane organization →	+0.053	+0.738	<.001	<.001	3	12
LIVER	Endoplasmic reticulum to cytosol transport →	+0.130	+0.962	.001	.002	3	12
LIVER	Retrograde protein transport, ER to cytosol →	+0.130	+0.962	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,553 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by BPNT2 expression — OESOPHAGUS

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