BPNT2

Across TCGA cell cohorts, BPNT2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BPNT2-associated genes across cancer lineages are DDX25, OR6M1, and VAX1. Each is linked with BPNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPNT2-to-partner and partner-to-BPNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDX25 grouped by BPNT2-low versus BPNT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPNT2→partner) and Y-score (partner→BPNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DDX25 →	+0.126	+3.254	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR6M1 →	+0.058	+5.228	<.001	.005	3	1
LARGE_INTESTINE	VAX1 →	+0.550	+2.782	.003	.007	2	1
LARGE_INTESTINE	FAM205A →	+0.014	+3.029	.006	.003	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

DDX25 by BPNT2 expression — LARGE_INTESTINE

Explore this box plot interactively →