Across TCGA patient cohorts, BPIFB4 mutation is significantly associated with the RNA expression of many other genes, with 2,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BPIFB4-associated genes across cancer lineages are RNU6-340P, DUSP3, and DCLRE1B. Each is linked with BPIFB4 in more than 3 cancer types. Because this analysis shows association rather than direction, both BPIFB4-to-partner and partner-to-BPIFB4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB4→partner) and Y-score (partner→BPIFB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-340P →	+0.331	+5.342	<.001	.002	3	4
UCEC	DUSP3 →	+0.405	+2.502	.002	.001	3	3
UCEC	DCLRE1B →	+0.490	+2.606	.001	.005	3	3
UCEC	RETREG3 →	+0.290	+4.000	.005	<.001	3	3
BRCA	RNA5SP204 →	+0.238	+5.038	<.001	.003	3	3
UCEC	ANKRD39 →	+0.252	+2.606	.006	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,277 associations by consensus.

Exploration

BPIFB4 survival (RNA) · tumor vs normal (RNA) · all BPIFB4 data types