BPIFB2

Across TCGA patient cohorts, BPIFB2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,081 significant associations in total. COAD shows the largest number of these associations.

The most reproducible BPIFB2-associated genes across cancer lineages are BPIFB6, MUC5B, and TFF3. Each is linked with BPIFB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both BPIFB2-to-partner and partner-to-BPIFB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BPIFB2 versus BPIFB6 in LUAD, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB2→partner) and Y-score (partner→BPIFB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BPIFB6 →	+0.279	+1.391	<.001	<.001	3	4
LUAD	MUC5B →	+1.962	+0.839	<.001	<.001	3	3
HNSC	TFF3 →	+2.426	+1.218	<.001	<.001	3	3
BRCA	TFF1 →	+2.874	+0.806	.002	.002	2	4
UCEC	SCGB3A1 →	+3.772	+1.510	.003	.002	3	3
UCEC	FAM3D →	+2.403	+2.090	.007	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,081 associations by consensus.

BPIFB2 vs BPIFB6 — LUAD

Explore this scatter interactively →