BPIFB2

Across TCGA cell cohorts, BPIFB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 896 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BPIFB2-associated GO terms across cancer lineages are Regulation of action potential, Regulation of metaphase/anaphase transition of cell cycle, and Response to L-phenylalanine derivative. Each is linked with BPIFB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BPIFB2-to-partner and partner-to-BPIFB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of action potential grouped by BPIFB2-low versus BPIFB2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB2→partner) and Y-score (partner→BPIFB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of action potential →	+0.117	+0.004	.009	.009	3	3
BREAST	Regulation of metaphase/anaphase transition of cell cycle →	-0.074	-1.956	.005	.005	3	3
BREAST	Response to L-phenylalanine derivative →	-0.115	-1.607	.001	.004	3	3
BREAST	Protein K48-linked ubiquitination →	-0.035	-1.366	.001	.006	3	3
BREAST	Atrial cardiac muscle cell to AV node cell communication →	-0.938	-1.802	<.001	<.001	3	3
BREAST	Ribonucleoside metabolic process →	-0.153	-1.552	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 896 associations by consensus.

Regulation of action potential by BPIFB2 expression — OESOPHAGUS

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