BPIFB1

Across TCGA patient cohorts, BPIFB1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,809 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BPIFB1-associated genes across cancer lineages are TFF3, AGR2, and SLC44A4. Each is linked with BPIFB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both BPIFB1-to-partner and partner-to-BPIFB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BPIFB1 versus TFF3 in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB1→partner) and Y-score (partner→BPIFB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TFF3 →	+3.506	+0.942	<.001	<.001	3	6
BRCA	AGR2 →	+3.159	+1.100	<.001	<.001	3	5
BRCA	SLC44A4 →	+2.362	+0.900	<.001	<.001	3	5
BRCA	PIP →	+2.816	+0.684	.004	.001	3	4
BRCA	TFF1 →	+3.934	+0.863	<.001	<.001	3	4
UCEC	SMIM31 →	+1.321	+1.077	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,809 associations by consensus.

BPIFB1 vs TFF3 — BRCA

Explore this scatter interactively →