BPIFB1

Across TCGA cell cohorts, BPIFB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,303 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BPIFB1-associated GO terms across cancer lineages are Negative regulation of hippocampal neuron apoptotic process, Positive regulation of iron ion transport, and Positive regulation of iron ion transmembrane transport. Each is linked with BPIFB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both BPIFB1-to-partner and partner-to-BPIFB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hippocampal neuron apoptotic process grouped by BPIFB1-low versus BPIFB1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB1→partner) and Y-score (partner→BPIFB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of hippocampal neuron apoptotic process →	+0.637	+0.608	.004	.009	3	7
LUNG_NSCLC_LUAD	Positive regulation of iron ion transport →	+0.896	+0.900	.003	.007	3	5
LUNG_NSCLC_LUAD	Positive regulation of iron ion transmembrane transport →	+0.896	+0.900	.003	.007	3	5
PANCREAS	Intracellular sodium ion homeostasis →	+0.151	+1.246	.003	.005	3	5
PANCREAS	Establishment of meiotic spindle orientation →	-0.123	-1.445	<.001	.001	3	5
OVARY	Negative regulation of macrophage inflammatory protein 1 alpha production →	-0.969	-1.008	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,303 associations by consensus.

Negative regulation of hippocampal neuron apoptotic process by BPIFB1 expression — SKIN

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