BPIFB1

Across TCGA cell cohorts, BPIFB1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible BPIFB1-associated genes across cancer lineages are GJA10, OR13C4, and OR8B12. Each is linked with BPIFB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFB1-to-partner and partner-to-BPIFB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJA10 grouped by BPIFB1-low versus BPIFB1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB1→partner) and Y-score (partner→BPIFB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	GJA10 →	+0.022	+5.169	<.001	.005	3	1
BREAST	OR13C4 →	+0.039	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR8B12 →	+0.067	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	CLEC4C →	+0.021	+4.947	.008	.001	3	1
LUNG_NSCLC_LUAD	TDRD15 →	+0.301	+4.734	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GJA10 by BPIFB1 expression — BREAST

Explore this box plot interactively →