BPIFA2

Across TCGA patient cohorts, BPIFA2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,655 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BPIFA2-associated genes across cancer lineages are THAP10, GLCE, and ESD. Each is linked with BPIFA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFA2-to-partner and partner-to-BPIFA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BPIFA2 versus THAP10 in HNSC, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFA2→partner) and Y-score (partner→BPIFA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	THAP10 →	-0.747	-1.333	<.001	.003	3	1
HNSC	GLCE →	-0.946	-1.960	<.001	.001	3	1
HNSC	ESD →	+0.750	+1.487	.003	.009	3	1
HNSC	TSPAN3 →	-0.707	-1.348	<.001	.003	3	1
HNSC	SAP18 →	+0.426	+1.349	.004	.003	3	1
HNSC	PXMP2 →	-0.733	-1.778	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,655 associations by consensus.

BPIFA2 vs THAP10 — HNSC

Explore this scatter interactively →