BPIFA2

Across TCGA cell cohorts, BPIFA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 437 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BPIFA2-associated GO terms across cancer lineages are Microtubule depolymerization, Purine ribonucleoside metabolic process, and Regulation of plasma cell differentiation. Each is linked with BPIFA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BPIFA2-to-partner and partner-to-BPIFA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule depolymerization grouped by BPIFA2-low versus BPIFA2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFA2→partner) and Y-score (partner→BPIFA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Microtubule depolymerization →	-0.099	-1.393	<.001	.005	3	3
BREAST	Purine ribonucleoside metabolic process →	-0.104	-0.899	<.001	.001	3	3
LUNG_NSCLC_LUAD	Regulation of plasma cell differentiation →	+0.093	+1.301	.003	.005	3	3
LUNG_NSCLC_LUAD	Positive regulation of plasma cell differentiation →	+0.092	+1.301	.002	.005	3	3
LUNG_NSCLC_LUAD	Negative regulation of NK T cell activation →	+0.101	+0.787	.001	.008	3	3
LUNG_NSCLC_LUAD	Oncogene-induced cell senescence →	-0.135	-0.906	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 437 associations by consensus.

Microtubule depolymerization by BPIFA2 expression — BREAST

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