BPIFA2

Across TCGA cell cohorts, BPIFA2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BPIFA2-associated genes across cancer lineages are CFHR2 and PRAMEF7. Each is linked with BPIFA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFA2-to-partner and partner-to-BPIFA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by BPIFA2-low versus BPIFA2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFA2→partner) and Y-score (partner→BPIFA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	2
BLOOD_Leukemia	PRAMEF7 →	+0.012	+5.539	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CFHR2 by BPIFA2 expression — LARGE_INTESTINE

Explore this box plot interactively →