BPHL

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BPHL RNA expression is significantly associated with the protein abundance of many other proteins, with 14,602 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BPHL-associated proteins across cancer lineages are WRNIP1, PRPF4B, and VSIR. Each is linked with BPHL in more than 8 cancer types. Because this analysis shows association rather than direction, both BPHL-to-partner and partner-to-BPHL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BPHL versus WRNIP1 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BPHL→partner) and Y-score (partner→BPHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVWRNIP1 →+0.649+0.690<.001<.00139
GBMPRPF4B →+0.392+0.454<.001<.00138
UCECVSIR →-0.669-0.377<.001<.00136
GBMWAS →-0.501-0.356<.001<.00136
BRCAWDFY4 →-0.419-0.441<.001<.00136
GBMXPO1 →+0.222+0.429<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,602 associations by consensus.

BPHL vs WRNIP1 — OV

Per-sample scatter of BPHL vs WRNIP1 in OV (Pearson r = 0.45).

Explore this scatter interactively →

Exploration