BPHL

Across TCGA patient cohorts, BPHL protein abundance is significantly associated with the RNA expression of many other genes, with 10,488 significant associations in total. COAD shows the largest number of these associations.

The most reproducible BPHL-associated genes across cancer lineages are CD69, IL18RAP, and CD244. Each is linked with BPHL in more than 4 cancer types. Because this analysis shows association rather than direction, both BPHL-to-partner and partner-to-BPHL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BPHL versus CD69 in LSCC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPHL→partner) and Y-score (partner→BPHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CD69 →	-1.114	-0.525	<.001	<.001	3	5
LSCC	IL18RAP →	-1.017	-0.630	<.001	<.001	3	5
BRCA	CD244 →	-0.714	-0.603	<.001	<.001	3	5
UCEC	GMFG →	-1.060	-0.444	<.001	<.001	3	5
BRCA	GIMAP6 →	-0.687	-0.331	<.001	.001	3	5
LSCC	STX11 →	-0.655	-0.547	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,488 associations by consensus.

BPHL vs CD69 — LSCC

Explore this scatter interactively →