BPHL

Across TCGA cell cohorts, BPHL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,353 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BPHL-associated GO terms across cancer lineages are Homocysteine metabolic process, Negative regulation of CD4-positive, alpha-beta T cell activation, and Transport along microtubule. Each is linked with BPHL in more than 11 cancer types. Because this analysis shows association rather than direction, both BPHL-to-partner and partner-to-BPHL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Homocysteine metabolic process grouped by BPHL-low versus BPHL-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BPHL→partner) and Y-score (partner→BPHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Homocysteine metabolic process →	+0.111	+0.643	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of CD4-positive, alpha-beta T cell activation →	-0.065	-0.514	.001	.006	3	9
STOMACH	Transport along microtubule →	+0.042	+0.737	.004	.005	2	10
BONE	Cell adhesion mediated by integrin →	-0.202	-0.847	<.001	<.001	3	8
BONE	Multi-multicellular organism process →	-0.119	-0.993	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of DNA repair →	+0.034	+0.520	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,353 associations by consensus.

Homocysteine metabolic process by BPHL expression — LARGE_INTESTINE

Explore this box plot interactively →