BORCS8

Across TCGA cell cohorts, BORCS8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,837 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BORCS8-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Mitotic chromosome condensation, and Peptidyl-proline modification. Each is linked with BORCS8 in more than 11 cancer types. Because this analysis shows association rather than direction, both BORCS8-to-partner and partner-to-BORCS8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by BORCS8-low versus BORCS8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BORCS8→partner) and Y-score (partner→BORCS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.131	+0.605	.009	.005	3	12
PANCREAS	Mitotic chromosome condensation →	+0.133	+0.608	<.001	<.001	3	11
LARGE_INTESTINE	Peptidyl-proline modification →	+0.112	+0.670	<.001	<.001	3	11
BREAST	Spliceosomal tri-snRNP complex assembly →	+0.116	+1.102	<.001	<.001	3	11
SKIN	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.116	+0.710	<.001	.002	3	11
SOFT_TISSUE	DNA replication proofreading →	+0.139	+0.583	.009	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,837 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by BORCS8 expression — BONE

Explore this box plot interactively →