Across TCGA pan-cancer cohorts, BORCS8-MEF2B Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated BORCS8-MEF2B data layer compared with 23 for mass-spec protein.
The strongest signal is observed in esophageal carcinoma (ESCA), where higher BORCS8-MEF2B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BORCS8-MEF2B expression acts as an unfavorable survival marker.
ESCA are the cancer types where BORCS8-MEF2B Mutation most reproducibly stratifies survival.