BORCS8-MEF2B

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BORCS8-MEF2B Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated BORCS8-MEF2B data layer compared with 23 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher BORCS8-MEF2B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BORCS8-MEF2B expression acts as an unfavorable survival marker.

ESCA are the cancer types where BORCS8-MEF2B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCAOSMedianAll0.2220.680.0316view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

BORCS8-MEF2B–ESCA (OS)

Kaplan–Meier survival curve for BORCS8-MEF2B mutant vs wild-type samples in ESCA.

Open the ESCA breakdown →

Exploration