BORCS7

Across TCGA cell cohorts, BORCS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,539 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BORCS7-associated GO terms across cancer lineages are Regulation of vesicle size, Regulation of endosome size, and Post-Golgi vesicle-mediated transport. Each is linked with BORCS7 in more than 10 cancer types. Because this analysis shows association rather than direction, both BORCS7-to-partner and partner-to-BORCS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vesicle size grouped by BORCS7-low versus BORCS7-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BORCS7→partner) and Y-score (partner→BORCS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of vesicle size →	+0.078	+0.678	.001	<.001	3	11
SOFT_TISSUE	Regulation of endosome size →	+0.078	+0.581	<.001	<.001	3	10
BREAST	Post-Golgi vesicle-mediated transport →	+0.075	+0.823	<.001	<.001	3	10
BREAST	Golgi to plasma membrane transport →	+0.079	+0.794	<.001	<.001	3	10
BREAST	Golgi vesicle transport →	+0.064	+0.839	<.001	<.001	3	8
KIDNEY	Regulation of lysosome size →	+0.158	+0.845	.002	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,539 associations by consensus.

Regulation of vesicle size by BORCS7 expression — LUNG_SCLC

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