Across TCGA patient cohorts, BORCS6 protein abundance is significantly associated with the RNA expression of many other genes, with 13,278 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BORCS6-associated genes across cancer lineages are NEK2, UBE2T, and CKS2. Each is linked with BORCS6 in more than 6 cancer types. Because this analysis shows association rather than direction, both BORCS6-to-partner and partner-to-BORCS6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BORCS6→partner) and Y-score (partner→BORCS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NEK2 →	-0.962	-0.233	.003	.001	3	7
HNSC	UBE2T →	-1.267	-0.281	<.001	<.001	3	7
OV	CKS2 →	-1.038	-0.324	<.001	<.001	3	6
HNSC	NUF2 →	-1.030	-0.223	<.001	<.001	3	6
OV	TNFSF13 →	+0.632	+0.279	.003	<.001	3	6
GBM	PBK →	-1.327	-0.289	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,278 associations by consensus.

Exploration

BORCS6 survival (RNA) · tumor vs normal (RNA) · all BORCS6 data types