BORCS6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BORCS6 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BORCS6-associated genes across cancer lineages are MIR6857, MIR5707, and TRAJ43. Each is linked with BORCS6 in more than 1 cancer types. Because this analysis shows association rather than direction, both BORCS6-to-partner and partner-to-BORCS6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BORCS6→partner) and Y-score (partner→BORCS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6857 →+0.617+4.943<.001<.00132
UCECMIR5707 →+0.391+4.442.001.00732
COADTRAJ43 →+0.887+3.831.002.00731
COADMTND5P27 →+0.123+5.332<.001.00231
COADLINC02620 →+0.281+3.754.001.00831
COADOR51R1P →+0.209+4.602<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

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