Across TCGA cell cohorts, BORCS6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BORCS6-associated genes across cancer lineages are DRD3, LCE1F, and CD300H. Each is linked with BORCS6 in more than 1 cancer types. Because this analysis shows association rather than direction, both BORCS6-to-partner and partner-to-BORCS6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BORCS6→partner) and Y-score (partner→BORCS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DRD3 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	LCE1F →	+0.165	+5.415	<.001	.004	3	1
LARGE_INTESTINE	CD300H →	+0.052	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

BORCS6 survival (RNA) · tumor vs normal (RNA) · all BORCS6 data types